Publications

Scientific Articles

 

YEAR 2009

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Nakamura Y, Xing Y, Sasano H, Rainey WE. The mediator complex subunit 1 enhances transcription of genes needed for adrenal androgen production. Endocrinology. 2009 Sep;150(9):4145-53.

Prodoehl MJ, Hatzirodos N, Irving-Rodgers HF, Zhao ZZ, Painter JN, Hickey TE, Gibson MA, Rainey WE, Carr BR, Mason HD, Norman RJ, Montgomery GW, Rodgers RJ. Genetic and gene expression analyses of the polycystic ovary syndrome candidate gene fibrillin-3 and other fibrillin family members in human ovaries. Mol Hum Reprod. 2009 Aug 19.

Nakamura Y, Hornsby PJ, Casson P, Morimoto R, Satoh F, Xing Y, Kennedy MR, Sasano H, Rainey WE. Type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) contributes to testosterone production in the adrenal reticularis. J Clin Endocrinol Metab. 2009 Jun;94(6):2192-8.

Nogueira EF, Bollag WB, Rainey WE. Angiotensin II regulation of adrenocortical gene transcription. Mol Cell Endocrinol. 2009 Apr 29;302(2):230-6.

Nogueira EF, Xing Y, Morris CA, Rainey WE. Role of angiotensin II-induced rapid response genes in the regulation of enzymes needed for aldosterone synthesis. J Mol Endocrinol. 2009 Apr;42(4):319-30.

Xing Y, Nakamura Y, Rainey WE. G protein-coupled receptor expression in the adult and fetal adrenal glands. Mol Cell Endocrinol. 2009 Mar 5;300(1-2):43-50.

Ye P, Nakamura Y, Lalli E, Rainey WE. Differential effects of high and low steroidogenic factor-1 expression on CYP11B2 expression and aldosterone production in adrenocortical cells. Endocrinology. 2009 Mar;150(3):1303-9.

Nakamura Y, Gang HX, Suzuki T, Sasano H, Rainey WE. Adrenal changes associated with adrenarche. Rev Endocr Metab Disord. 2009 Mar;10(1):19-26.

Xing Y, Saner-Amigh K, Nakamura Y, Hinshelwood MM, Carr BR, Mason JI, Rainey WE. The farnesoid X receptor regulates transcription of 3beta-hydroxysteroid dehydrogenase type 2 in human adrenal cells. Mol Cell Endocrinol. 2009 Feb 27;299(2):153-62.

Nakamura Y, Vargas Morris C, Sasano H, Rainey WE. DAX-1A (NR0B1A) expression levels are extremely low compared to DAX-1 (NR0B1) in human steroidogenic tissues. Horm Metab Res. 2009 Jan;41(1):30-4.

Ye P, Yamashita T, Pollock DM, Sasano H, Rainey WE. Contrasting effects of eplerenone and spironolactone on adrenal cell steroidogenesis. Horm Metab Res. 2009 Jan;41(1):35-9.

 

YEAR 2008

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Carneiro FS, Nunes KP, Giachini FR, Lima VV, Carneiro ZN, Nogueira EF, Leite R, Ergul A, Rainey WE, Clinton Webb R, Tostes RC. Activation of the ET-1/ETA pathway contributes to erectile dysfunction associated with mineralocorticoid hypertension. J Sex Med. 2008 Dec;5(12):2793-807.

Parmar J, Key RE, Rainey WE. Development of an adrenocorticotropin-responsive human adrenocortical carcinoma cell line. J Clin Endocrinol Metab. 2008 Nov;93(11):4542-6.

Rainey WE, Nakamura Y. Regulation of the adrenal androgen biosynthesis. J Steroid Biochem Mol Biol. 2008 Feb;108(3-5):281-6. Review.

 

YEAR 2007

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Nogueira EF, Vargas CA, Otis M, Gallo-Payet N, Bollag WB, Rainey WE. Angiotensin-II acute regulation of rapid response genes in human, bovine, and rat adrenocortical cells. J Mol Endocrinol. 2007 Dec;39(6):365-74.

Nakamura Y, Aoki S, Xing Y, Sasano H, Rainey WE. Metastin stimulates aldosterone synthesis in human adrenal cells. Reprod Sci. 2007 Dec;14(8):836-45.

Beshay VE, Havelock JC, Sirianni R, Ye P, Suzuki T, Rainey WE, Carr BR. The machanism for protein kinase C inhibition of androgen production and 17alpha-hydroxylase expression in a theca cell tumor model. J Clin Endocrinol Metab. 2007 Dec;92(12):4802-9.

Ye P, Mariniello B, Mantero F, Shibata H, Rainey WE. G-protein-coupled receptors in aldosterone-producing adenomas: a potential cause of hyperaldosteronism. J Endocrinol. 2007 Oct;195(1):39-48.

Rehman KS, Sirianni R, Parker CR Jr, Rainey WE, Carr BR. The regulation of adrenocorticotrophic hormone receptor by corticotropin-releasing hormone in human fetal adrenal definitive/transitional zone cells. Reprod Sci. 2007 Sep;14(6):578-87.

Beshay VE, Carr BR, Rainey WE. The human fetal adrenal gland, corticotropin-releasing hormone, and parturition. Semin Reprod Med. 2007 Jan;25(1):14-20. Review.

 

YEAR  2006

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Saner-Amigh K, Mayhew BA, Mantero F, Schiavi F, White PC, Rao CV, Rainey WE.
Elevated expression  of luteinizing hormone receptor in aldosterone-producing adenomas. J Clin Endocrinol Metab. 2006 Mar;91(3):1136-42.   

Havelock JC, Rainey WE, Bradshaw KD, Carr BR. The post-menopausal ovary displays a unique pattern of steroidogenic enzyme expression. Hum Reprod. 2006 Jan;21(1):309-17.

 

YEAR  2005

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Sirianni R, Mayhew BA, Carr BR, Parker CR Jr, Rainey WE. Corticotropin-releasing hormone (CRH) and urocortin act through type 1 CRH receptors to stimulate dehydroepiandrosterone sulfate production in human fetal adrenal cells. J Clin Endocrinol Metab. 2005 Sep;90(9):5393-400.   

Bassett MH, Mayhew B, Rehman K, White PC, Mantero F, Arnaldi G, Stewart PM, Bujalska I, Rainey WE.  Expression profiles for steroidogenic enzymes in adrenocortical disease. J Clin Endocrinol Metab. 2005 Sep;90(9):5446-55.  

Seely J, Amigh KS, Suzuki T, Mayhew B, Sasano H, Giguere V, Laganiere J, Carr BR, Rainey WE. Transcriptional regulation of dehydroepiandrosterone sulfotransferase (SULT2A1) by estrogen-related receptor alpha. Endocrinology. 2005 Aug;146(8):3605-13.

Havelock JC, Keller P, Muleba N, Mayhew BA, Casey BM, Rainey WE, Word RA.
Human myometrial gene expression before and during parturition. Biol Reprod. 2005 Mar;72(3):707-19.  

White PC, Rainey WE. Editorial: polymorphisms in CYP11B genes and 11-hydroxylase activity. J Clin Endocrinol Metab. 2005 Feb;90(2):1252-5.

Kurihara I, Shibata H, Kobayashi S, Suda N, Ikeda Y, Yokota K, Murai A, Saito I, Rainey WE, Saruta T. Ubc9 and Protein Inhibitor of Activated STAT 1 Activate Chicken Ovalbumin Upstream Promoter-Transcription Factor I-mediated Human CYP11B2 Gene Transcription. J Biol Chem. 2005 Feb 25;280(8):6721-30.   

Havelock JC, Smith AL, Seely JB, Dooley CA, Rodgers RJ, Rainey WE, Carr BR. The NGFI-B family of transcription factors regulates expression of 3beta-hydroxysteroid dehydrogenase type 2 in the human ovary. Mol Hum Reprod. 2005 Feb;11(2):79-85.  
 
Sirianni R, Rehman KS, Carr BR, Parker CR Jr, Rainey WE.Corticotropin-releasing hormone directly stimulates cortisol and the cortisol biosynthetic pathway in human fetal adrenal cells. J Clin Endocrinol Metab. 2005 Jan;90(1):279-85.  
 
Saner KJ, Suzuki T, Sasano H, Pizzey J, Ho C, Strauss JF 3rd, Carr BR, Rainey WE. Steroid sulfotransferase 2A1 gene transcription is regulated by steroidogenic factor 1 and GATA-6 in the human adrenal. Mol Endocrinol. 2005 Jan;19(1):184-97.  

 

YEAR  2004

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Shibata H, Kobayashi S, Kurihara I, Suda N, Yokota K, Murai A, Ikeda Y, Saito I, Rainey WE, Saruta T. COUP-TF and transcriptional co-regulators in adrenal steroidogenesis.(No PDF available) Endocr Res. 2004 Nov;30(4):795-801.

 Bassett MH, White PC, Rainey WE.  A role for the NGFI-B family in adrenal zonation and adrenocortical disease. (No PDF available.) Endocr Res. 2004 Nov;30(4):567-74.

Havelock JC, Auchus RJ, Rainey WE. The rise in adrenal androgen biosynthesis: adrenarche. Semin Reprod Med. 2004 Nov;22(4):337-47.

Rainey WE, Rehman KS, Carr BR. The human fetal adrenal: making adrenal androgens for placental estrogens. Semin Reprod Med. 2004 Nov;22(4):327-36.

Rainey WE, Carr BR. Adrenal androgens in human physiology. Semin Reprod Med. 2004 Nov;22(4):279-80. No PDF available.

Rainey WE, Rehman KS, Carr BR. Fetal and maternal adrenals in human pregnancy.
Obstet Gynecol Clin North Am. 2004 Dec;31(4):817-35.

Havelock JC, Rainey WE, Carr BR. Ovarian granulosa cell lines. Mol Cell Endocrinol. 2004 Dec 30;228(1-2):67-78.

Rainey WE, Saner K, Schimmer BP. Adrenocortical cell lines. Mol Cell Endocrinol. 2004 Dec 30;228(1-2):23-38.

Lu L, Suzuki T, Yoshikawa Y, Murakami O, Miki Y, Moriya T, Bassett MH, Rainey WE, Hayashi Y, Sasano H. Nur-related factor 1 and nerve growth factor-induced clone B in human adrenal cortex and its disorders. J Clin Endocrinol Metab. 2004 Aug;89(8):4113-8.

Bassett MH, Suzuki T, Sasano H, De Vries CJ, Jimenez PT, Carr BR, Rainey WE. The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase. implications for the control of adrenal functional zonation. J Biol Chem. 2004 Sep 3;279(36):37622-30.  .

Kim JW, Peng N, Rainey WE, Carr BR, Attia GR. Liver receptor homolog-1 regulates the expression of steroidogenic acute regulatory protein in human granulosa cells. J Clin Endocrinol Metab. 2004 Jun;89(6):3042-7.

Bassett MH, White PC, Rainey WE. The regulation of aldosterone synthase expression.
Mol Cell Endocrinol. 2004 Mar 31;217(1-2):67-74.

Correa RV, Domenice S, Bingham NC, Billerbeck AE, Rainey WE, Parker KL, Mendonca BB. A microdeletion in the ligand binding domain of human steroidogenic factor 1 causes XY sex reversal without adrenal insufficiency.J Clin Endocrinol Metab. 2004 Apr;89(4):1767-72.

Auchus RJ, Rainey WE. Adrenarche - physiology, biochemistry and human disease.
Clin Endocrinol (Oxf). 2004 Mar;60(3):288-96.

Bassett MH, Suzuki T, Sasano H, White PC, Rainey WE. The orphan nuclear receptors NURR1 and NGFIB regulate adrenal aldosterone production. Mol Endocrinol. 2004 Feb;18(2):279-90.   

 

YEAR  2003

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YEAR  2002

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