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  Clinical Neurovascular Program
The Mission of the cerebrovascular division at MCG is to  promote the education, diagnosis and treatment of patients with a variety of cerebrovascular disorders.  Our division consists of a cerebrovascular neurosurgeon trained in both open vascular and endovascular techniques and an interventional neuroradiologist.  These two individuals work closely together while treating these patients.  The division has a cost center that is separate from both neurosurgery and radiology, and the clinics for these two specialists are conducted at the same time and in  
the same location.  This has greatly promoted a close working relationship that we believe enhances our ability to provide the best possible patient care.  Other key components to the program are the stroke neurology team, operative nursing staff, neuroscience unit and nursing staff, neuroscience clinic staff, bipanar angiography suite, gamma knife unit, BrainLab stereotactic unit and new angiography recovery suite.  We treat the gamut of cerebrovascular diseases, a fraction of which is outlined below:
 
Cerebral Aneurysms

Angiograms over time of a typical aneurysm being treated via coil implementation

Cerebral aneurysms are present in up to 5% of the population.  While an estimated 1% of the population will experience an aneurysmal bleed, up to a third of these patients will die within days of the hemorrhage if untreated.  We provide the full spectrum of treatment of both unruptured and ruptured aneurysms including surgical clip ligation with intraoperative arteriogram, and coil embolization (shown above).  The stent-coil technique has expanded the role of coil embolization in aneurysms with wide necks that might not otherwise be suitable for coiling.   



click to view
Quicktime movie
WARNING: large file (6.2megs)

 
Cerebral Arteriovenous Malformations
Cerebral AVMs are vascular anomalies consisting of fistulous connections between arteries and veins without a normal intervening capillary bed.  Most of these lesions are considered congenital and they typically present by age 40.  The most common presentation is intracranial hemorrhage (65%), followed by seizures (15-35%), headaches (15%), and focal neurological deficits (less than 10% of cases).  The rupture rate is 3-4% per year.  The treatment options include surgical resection, embolization, stereotactic radiosurgery or a combination, but the decision to treat is often a complex one which factors in the age and health of the patient, presentation, characteristics of the lesion,
 


and treatment risks.
 
 

Photo of arteriovenous fistula case at MCG, 2005
click to view Windows Media Player movie (5.5megs)

Carotid Stenosis
While asymptomatic carotid stenosis carries a low annual risk of ipsilateral stroke of approximately 2%, the 2-year risk of stroke in patients with greater than 70% symptomatic stenosis is 21%.  When the plaque is ulcerated this risk steadily


  increases with increasing degrees of stenosis such that a 75% symptomatic stenosis with an ulcerated plaque carries a 26.3% 2-year risk of stroke while a 95% stenotic lesion carries a 73% risk.  The options for treatment include carotid endarterectomy and stenting with distal protection.  While endarterectomy is the most frequently performed technique, stenting is often the preferred treatment in patients with a high surgical risk such as those with contralateral occlusion, previous neck surgery, or previous radiation treatment.

Stroke
The approval by the NIH of the thrombolytic tPA greater expanded the treatment options for patients presenting with stroke.  The NINDS IV tPA trial demonstrated its safe and effective use if given within 3 hours after the onset of symptoms.  Unfortunately only 4% of stroke patients presents within this time window.  Those presenting with 6 hours may be eligible for intra-arterial thrombolysis.

Cerebral Vascular Insufficiency
Cerebral insufficiency may occur in a variety of patient subgroups such as those with moya moya disease, sickle cell disease, cervical or cerebral vessel occlusions.  Some patients who suffer from insuffiecient blood flow to the
Illustration of carotid endarterectomy and
stenting, courtesy of BNI
  hemispheres may be candidates for a revas- cularization procedure such as a superficial
temporal to middle cerebral arterybypass, a vein bypass, or an encephaloduro- arteriosynangiosis (EDAS).


Cerebral vascular insufficiency caused by Sickle Cell disease
 

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  © 2006 MCG

Questions and Comments to Cargill Alleyne, Jr. M.D.  


 September 26, 2006


Department of Neurosurgery  |  Medical College of Georgia