Mechanism of Estrogen Action in Human Coronary Artery Smooth Muscle Cells.
American Heart Association 2004-2007.
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1992-1994: National Natural Science Foundation of China Grant, Co-investigator.
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1993-1995: Education of Commission of Liao Ning Province Grant.
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1996-1997: Fellowship, Education Commission For Foreign Medical Graduates (ECFMG).
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1998: Outstanding Research Work Award, National Education Commission Of China.
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1999: Model Faculty Member, Dalian Medical University.
Guichun Han, Maozhang Lin Role of brain cholinergic system on diuresis and natriuresis induced by volume expansion in rats Chinese Journal of Physiological Sci 1993, 91,76-82.
Bo Zhang, Guichun Han, Maozhang Lin Role of Hypothalamus PVN in diuresis and natriuresis induced by volume expansion in rabbits. Caps News Communication 1995, 14 Suppl. 31
Wang Yong, Guichun Han, Maozhang Lin Role of spinal a adrenoceptor in the inhibition of renal sympathetic nerve activity and natriuresis induced by blood volume expansion in rabbits. Acta Physiologica Sinica 1997, 49 6 ,679-684
Guichun Han, Jonathan P. Kryman, Patricia J. P. McMillin, Richard E. White, and Gerald O. Carrier A Novel transduction mechanism mediating dopamine-induced vascular relaxation: opening of BKCa channels via cyclic AMP-induced stimulation of the cyclic GMP-dependent protein kinase. Journal of Cardiovascular Pharmacology 1999, 34, 619-27.
Richard E. White, Jonathan P. Kryman, Abdalla M. El-Mowafy, Guichun Han, Gerald O. Carrier Cyclic AMP-dependent vasodilators cross-activated the GMP-dependent protein kinase to stimulate BKCa channel activity in coronary
artery smooth muscle cells. Circulation Research 2000, 86, 897-905.
Guichun Han, Patricia JPMcMillin, Richard E. White Dopamine stimulates BKCa channel activity in smooth muscle from coronary arteries. C. J. Pharmacology and Toxicology 2000, 242, 25-32.
Guichun Han, Richard E. White Mechanism of the activation of BKCa channel Induced by dopamine Journal of Chinese Application Physiology 2000, 16 (1) 33-36
Richard E. White, Guichun Han, Melissa Maunz, Christiana Dimitropoulou, Abdalla M. El-Mowafy, Robert S. Barlow, John D. Catravas, Connie Sneed,
Gerald O. Carrier, Shu Zhu, Xiuping Yu Endothelium-independent effect of
estrogen on Ca2+-activated K+ channels in human coronary artery smooth
muscle cells Cardiovascular Research 2002, 53: 650-661
Allison W. Miller, Christiana Dimitropoupou, Guichun Han, Richard E. White, David W. Busija, and Gerald O, Carrier Epoxyeicosatrienoic acid-induced
relaxation is impaired insulin resistance. Am J Physiol 2001, 281; H1524-
H1531
Christiana Dimitropoulou, Guichun Han, Allison W. Miller, Mariela Molero, Leslie C. Fuchs, Richard E. White, and Gerald O. Carrier Potassium (BKCa)
currents are reduced in microvascular smooth muscle cells from insulin-
resistant rats. American Journal of Physiology 2002, 282; H908-H917
Zhu, S., G. Han, and R.E. White. Mechanisms of cardiovascular protection by PGE2 in human coronary artery: cAMP opens BKCa channels via PKG. J. Vascular Res. 39:477-488, 2002.
Barman, S.A., S. Zhu, G. Han, and R.E. White. Cyclic AMP activates BKCa
channels in pulmonary arterial smooth muscle via cGMP-dependent protein
kinase. Am J Physiol Lung Cell Mol Physiol 284: L1004-L1011, 2003.
White, R. E., Han, G., Dimitropoulou, C. and Zhu S. Estrogen-induced contraction of coronary arteries is mediated by superoxide generated in
vascular smooth muscle. Am J Physiol Heart Circ Physiol 289: H1468-H1475,
2005.
Han, G., Yu, X., Lu, L., Li, S., Ma, H., Zhu, S., Cui, X and White R.E. Estrogen receptor alpha mediates acute K channel stimulation in human coronary artery smooth muscle cells. JPET 316: 1025-1030, 2006
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