Glioblastoma Evaluation with F18FDG
- Amanda Brautigan, CNMT, RT(N)
- Senior Student NMT, Medical College of Georgia
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- Rufus Poole, CNMT, Chief Technologist
- Emory Univeristy Hospital, Department of Nuclear Medicine
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- Mary Anne Owen, MHE, RT(N)
- Program Director, Nuclear Medicine Technology
- Medical College of Georgia
Patient History:
53 year old white male with history of 5x4x5 cm glioblastoma in the right parietal posterior frontal lobe seen on MRI. This caused some brain edema. The mass was initially found in August of 2001. A craniotomy was performed in the same month and then radiation therapy was delivered to the right hemisphere.
Findings:
There is a large photopenic defect seen in the right parietal lobe with surrounding rim uptake. There is diffuse decreased uptake throughout the right hemisphere consistent with post-radiation change. The rim uptake is highly metabolic which indicates residual/recurrent tumor.
A
second MRI with and without contrast was performed after resection. There
was an improvement in the edema but there was also some signal consistent with
residual tumor. On MRI performed in March of 2002 a small mass was noted
in the right parietal lobe consistent with progression of glioblastoma.
This recurrent mass is believed to be necrotic. It would
be useful to see accompanying MR images if available.
Radiopharmacy:
10.5
mCi of F18 FDG were injected intravenously and the patient sat alone in a dim
room for 45 minutes. The images were reconstructed in transaxial
sagittal and coronal planes and sliced on the cantomeatal line.
Patient
Preparation
The
patient was set up with the usual warm, molded facial mask for stable
positioning. Is this a one size fits all
apparatus? What is it, and how is it molded?
Instrumentation
What imaging system was used?
3D imaging of the brain was performed with septa removed and a special shield in place to cut down on scatter from the body.
How is processing
and instrumentation different for PET as compared to SPECT?
-
May 2002
Positioning
What would be the special considerations of positioning to obtain "3D imaging of the brain" as described above?
How is the posiitoning different from SPECT imaging, if at all?
Processing
The images were reconstructed in
transaxial sagittal and coronal planes and sliced on the cantomeatal line.