Section of Pediatric Hematology/Oncology
Protocols Open For Accruals
Lymphoma Studies:
ANHL0121
A Phase II Study of Rituximab (IND#7028) and Ifosfamide, Carboplatin and
Etoposide (ICE) Chemotherapy in Children with Recurrent/Refractory B-cell
(CD20+) Non-Hodgkin Lymphoma and B-cell Acute Lymphoblastic Leukemia.
ANHL0131
A Phase III Trial of Treatment of Advanced-Stage Anaplastic Large Cell Lymphoma
(ALCL) with Standard APO (Doxorubicin, Prednisone, Vincristine) versus Consolidation
with a Regimen Including Vinblastine
A5971
A Randomized Phase III Study for the Treatment of Newly Diagnosed Disseminated
Lymphoblastic Lymphoma or Localized Lymphoblastic Lymphoma
Leukemia Study:
AALL0232
High Risk B-precursor Acute Lymphoblastic Leukemia
COG AALL0331
Standard Risk B-Precursor Acute Lymphoblatic Leukemia
AALL00P2
T-CELL PILOT PROTOCOL. The Use of Modified BFM +/- Compound 506U78 (Nelarabine)
(NSC# 686673, IND #52611) in an Intensive Chemotherapy Regimen for the Treatment
of T-Cell Leukemia
AALL03N1
Understanding the Role of Adherence and Ethnic Differences in Survival After
Childhood ALL
AALL03B1
Classification of Acute Lymphoblastic Leukemia
Hodgkin Study:
AHOD0031
A Phase III Study of Dose-Intensive, Response-Based Chemotherapy and Radiation
Therapy for Children and Adolescents with Newly Diagnosed Intermediate Risk
Hodgkin Disease
Neuroblastoma Studies:
ANBL00P2
Perinatal Neuroblastoma Expectant Observation A Children's Oncology Group
Pilot Study.
ANBL00B1
Neuroblastoma Biology Studies.
Neuro-Oncology Studies:
ACNS0423
A Phase II Study of Concurrent Radiation and Temozolomide Followed by Temozolomide
And Lomustine (CCNU) in the Treatment of Children with High Grade Glioma
ACCL0422
Adderall XR Versus Concerta for Cancer Treatment-Related Neurocognitive
Sequelae and Depression in Pediatric Patients a Randomized Phase II Study
ACNS0331
A Study Evaluating Limited Target Volume Boost Irradiation and Reduced Dose
Craniospinal Radiotherapy (18.00 Gy) and Chemotherapy in Children with Newly
Diagnosed Standard Risk Medulloblastoma: A Phase III Double Randomized Trial.
ACNSO2B3
A Children's Oncology Group Protocol for Collecting and Banking Pediatric
Brain Tumor Research Specimens.
P9962
A Phase II Study of Intrathecal Topotecan (NSC #609699) in Patients with
Refractory Meningeal Malignancies.
Ewing Sarcoma Studies:
AEWS02P1
A Pilot Study of Low-Dose Antiangiogenic Chemotherapy in Combination with
Standard Multiagent Chemotherapy for Patients with Newly Diagnosed Metastatic
Ewing Sarcoma Family of Tumors
COG AEWS02B1
A Groupwide Biology and Banking Study for Ewing Sarcoma
Osteosarcoma Study:
COG P985
Osteosarcoma Biology Protocol: Companion to Group-Wide Therapeutic Studies.
Rhabdomysarcoma Studies:
COG ARST0331
Vincristine, Dactinomycin, and Lower Doses of Cyclophosphamide With or Without
Radiation Therapy for Patients with Newly Diagnosed Low-Risk Embryonal/Botryoid
Rhabdomyosarcoma
D9902
A COG Soft Tissue Sarcoma Biology and Banking Protocol.
Other Study:
ACCL0423
The Effect of Cyproheptadine Hydrochloride (Periactin) and Megestrol
Acetate (Megace) on Weight in Children with Cancer/Treatment Related
Cachexia.
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