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Continuity Clinic Notebook:

Chapter III. Adolescent Issues

Chapter 3 Index

A. General

B. Skin

C. Orthopedics

D. Genitourinary:
--Hormonal Contraception for Adolescents

--Dysmenorrhea

 

Dysfunctional Uterine Bleeding

Reda Bassali, MD

Definition: Prolonged bleeding from the uterine endometrium that is unrelated to an organic lesion. Bleeding is painless and irregular.  Secondary to anovulatory cycles which can occur in 50% of adolescents following menarche.

Issue

Normal

Abnormal: Hgb must be checked!

Duration of flow

2-8 days

< 2 days; > 8 days

Cycle length

21-40 days

< 21 days; > 40 days

Blood loss

20-80 cc (avg 30cc)

> 80 cc

Length of time irregular

Up to 2 years (anovulatory)

> 2 years

Differential Diagnosis of Dysfunctional Uterine Bleeding: 1/4 hospitalized adolescents = organic

  1. Pregnancy complications: Ectopic, Abortion

  2. Genital Infections: Vaginitis, Cervicitis, PID, and Foreign Body

  3. Endocrinopathies: Thyroid, hyperprolactinemia

  4. Drugs: Oral contraceptives (missed pills); seizure medications

  5. Coagulation disorders such as VW disease, ITP.

  6. Neoplasms: cervical polyps, leiomyoma, and carcinoma

  7. Chronic Illness: liver failure, renal failure

  8. Hypothalamic dysfunction: stress, excessive exercise, weight loss.

Laboratory Workup of Dysfunctional Uterine Bleeding:

  1. CBC - must check Hemoglobin: if < 12 = moderate; if < 10 gms = severe.

  2. Pregnancy test

  3. PT, PTT, Bleeding time, VW factor level

  4. If chronic anovulation: LH/FSH

Treatment:

  1. Education, explanation, reevaluate periodically

  2. If mild (Hemoglobin > 12): treat with oral contraceptives if sexually active only reassurance if not sexually active

  3. If moderate (Hemoglobin between 10 and 12): give iron, oral contraceptives (Ovral) combine with treatment with NSAIDs (see dysmenorrhea chart)

  4. If severe (Hemoglobin < 10): May need to hospitalize, transfuse, and give iron. Give oral contraceptives q 6 hours until bleeding stops x 24 hours then taper to 1x/day over 5-7 days. Give IV Premarin

Written 5/01

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Department of Pediatrics  |  Medical College of Georgia
Please email comments, suggestions or questions to:
John T.  Benjamin M.D., 
jbenj@mcg.edu

February 27, 2004