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Continuity Clinic Notebook:

Chapter II. The Evaluation of the Sick Child

Chapter 2 Index

A. Evaluation by system:

 

Definition and Treatment of Fever 

General Information

Definition of Fever: The general consensus is that temps of > 100.6 degrees rectally; >99.4 degrees axillary, and > 98.6 degrees orally (though diurnal variation make some say >99.0 degrees orally) constitute fever. Fever Phobia: A condition of parents, grandparents, nurses, and doctors!  It should be avoided at all costs.

Pathogenesis of Fever: response of the CNS to endogenous pyrogenic cytokines (e.g. interleukin1) which also induce slow-wave sleep - ? reason for somnolence with fever. 

How Should a Temperature Be Measured?:  A Number of Choices.

  • Rectal temperature: considered the gold standard in child between birth and three years of  age.  However, some infrared tympanic temperatures more reliable in older children.
  • Ear temperatures are the quickest and technology has improved with these methods.  Some question of effect of cerumen interfering with this method. Not sure of reliability in children under 3 years of age. (J Peds: 98;133:471-473)
  • Strips on forehead: not a reliable way to check temperatures.
  • Pacifier thermometer: takes too long to be considered for routine office use - 3.5 minutes.  Must add 0.5 degrees F to be comparable to rectal temperature. Useful at home.
  • Axillary temperature: First Years Comfortemp takes 20 readings/second, which are averaged to get final result in 3 seconds.  Infrared: accurate within 0.1 degree when compared to rectal. This new in 1997: Phone number: 800-533-6700
  • Parental touch: reliable in 79% of cases; 2nd study - accurate in 84% of cases.

Treatment of Fever: 

Why treat fever? Primary reason: comfort of child.  Theoretical reason to not treat under 102 degrees (helps fight infection); definitely poorer outcome if don’t treat fever over 104.

A. Medications: Parents will have preferences. Recommend: do not give both meds!

  • Acetaminophen is the standard, and still the first line med for the treatment of fever: dosage: 10-15 mg/kg every 4 hours: 15/kg is more effective in reducing fever

  • Ibuprofen dosage: 10 mg/kg every 6-8 hours: max: 40 mg/kg/24hrs Comparison of the two types of medication: No difference (AJDC 1992;146:626-32): Another article (European J of ClinPharm1994;46:197-201): Ibuprofen works better in the first four hours of treatment but not after that time. Combination of the two: Review article: (Clinical Pharmacy: 1992:11:1005-21) - 244 references

  • no evidence that combining Ibuprofen and Acetaminophen works better.

  • increased toxicity risk because of increased dosing errors: the two meds are given at different intervals, and parents forget  which meds they gave last;

  • increased likelihood of adverse reactions; Ibuprofen: gastritis, GI bleed, and dyspepsia

  • Acetaminophen alone is still the preferred treatment for fever.

B. General advice to give parents in treating fever:

  • dress the child lightly: do not bundle child up; keep room cool - not hot;
  • give plenty of liquids to drink; put child in a lukewarm bath for at least 30 minutes if child is uncomfortable.

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Department of Pediatrics  |  Medical College of Georgia
Please email comments, suggestions or questions to:
John T.  Benjamin M.D., 
jbenj@mcg.edu

February 27, 2004