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Bala Ambati, M.D. |
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| Specialty: | |||||||||||||||||
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Cornea Refractive surgery |
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| Title/Rank: | |||||||||||||||||
| Assistant Professor | |||||||||||||||||
| Education: | |||||||||||||||||
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B.A., Biology - 1991 New York University |
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Doctor of Medicine - 1995 Mount Sinai School of Medicine |
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Internal Medicine Residency - 1997 Beth Israel Medical School |
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Ophthalmology Residency - 2001 Massachusetts Eye & Ear Infirmary |
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| Fellowships: | |||||||||||||||||
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Cornea & Refractive Surgery - 2002 Duke University |
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| Certifications: | |||||||||||||||||
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American Board of Internal Medicine American Board of Ophthalmology - 2003 |
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| Interests: | |||||||||||||||||
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Clinically, Dr. Ambati’s practice consists of patients with complex corneal and anterior segment pathology, those interested in laser vision correction or refractive surgery, and general ophthalmic issues. He performs cornea transplants, LASIK, cataract extraction, and other procedures of the anterior segment of the eye. Additionally, Dr. Ambati devotes a significant portion of his time to research endeavors investigating the molecular mechanisms of angiogenesis, the growth of new blood vessels, in the cornea. He has demonstrated that the molecule angiostatin, a fragment of the blood protein plasminogen, can both inhibit and regress corneal neovascularization, the first demonstration of regression of established neovascularization in any tissue. He is currently investigating the molecular pathways of the angiogenic cascade in the cornea, specifically focusing on the intracellular and tissue level effects of angiopoietins and the Tie2 receptor on endothelial cell proliferation, white blood cell infiltration, and matrix metalloproteinase levels. He is also involved in characterizing the role of the enzyme IDO (indoleamine 2,3-dioxygenase) in cornea transplant tolerance and development of neovascularization. With respect to clinical research, Dr. Ambati is committed to constant analysis of results of cornea transplants, LASIK, cataract extraction, and other anterior segment procedures with a view towards optimization of patient outcomes. |
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| Selected Papers: | |||||||||||||||||
| 1. | Ambati, B.K., Joussen, A.M., Ambati, J., et al. Angiostatin inhibits and regresses corneal neovascularization. Arch Ophth. 2002 Aug; 120: 1063-8. | ||||||||||||||||
| 2. | Ambati, BK, Ambati, J, Joussen AM, et al. (2002). Sustained inhibition of corneal neovascularization by genetic ablation of CCR5. Inv Ophth Vis Sci. In press. | ||||||||||||||||
| 3. | Ambati BK, Joussen AM, Anand A, Adamis AP, Ambati, J (2002). Inhibition of corneal neovascularization by genetic ablation of CCR2. Submitted to Cornea. | ||||||||||||||||
| 4. | Ambati, BK & Carlson, AC (2002) Preventing LASIK Buttonholes. Rev Refract Surg. (Feb 2002) 29-30. | ||||||||||||||||
| 5. |
Ambati J, Ambati
BK. Age-related eye disease study caveats. Arch
Ophth. 2002; 120: 997. |
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| 6. | Husain D, Ambati B, Adamis AP, Miller JW. Mechanisms of age-related macular degeneration. Ophthalmol Clin North Am. Mar 2002 ; 15(1): 87-91. | ||||||||||||||||
| 7. | Ambati, B.K., Rizzo, J.F. (2001) Nonglaucomatous cupping of the optic disc. Intl. Ophth. Clin. 41(1):139-49. | ||||||||||||||||
| 8. | Ambati, B.K., Ambati, J., Azar, N., Stratton, L., Schmidt, E. (2000) Periorbital and orbital cellulitis after the advent of Haemophilus influenzae vaccination. Ophthalmology. 107: 1450-3. | ||||||||||||||||
| 9. | Shiuey, Y., Ambati, B.K., Adamis, A.P. (2000) Use of Topical Ketorolac Tromethamine in Viral Conjunctivitis. Ophthalmology. 107: 1512-7. | ||||||||||||||||
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Books & Chapters: |
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| 1. | Ambati, B.K., Smith, W.T., & Azer, M.T. (2001) The Residents’ Manual of Medicine. 528 pp. B.C. Decker: Hamilton, Ontario. | ||||||||||||||||
| 2. | Ambati, B.K., Azar, N. (2001) Pediatric Intraocular Lenses. In: Intraocular Lenses, Azar, D. (ed.). W.B. Saunders: New York, NY. | ||||||||||||||||
| 3. | Ambati, B.K., Strauss, L., Azar. D. (2001) Basic Optics for the LASIK surgeon. In: LASIK, Azar, D. (ed). W.B. Saunders. In press. | ||||||||||||||||
| 4. | Ambati, B.K., & Ambati, J. (1998) AIDS: The True Story – A Comprehensive Guide. (2nd edition) Foreword by Dr. Don DesJarlais, Beth Israel. 190 pp. 1st Books: Bloomington, IN. | ||||||||||||||||
| 5. | Ambati, B.K. & Ambati, J. (1989) AIDS: The True Story – A Comprehensive Guide. Foreword by Dr. John Bartlett, The Johns Hopkins University School of Medicine. 176 pp. BJ Publications: Baltimore, MD. | ||||||||||||||||
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Copyright 2007
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Please email comments, suggestions or questions to web manager |
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September 09, 2006 |
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