Titus H.J. Huisman
Hemoglobinopathy Laboratory

The Sickle Cell Center Laboratory at the Medical College of Georgia is an international testing and reference center for sickle cell disease, thalassemia and other hemoglobin disorders. The laboratory, one of few in the country that studies abnormal hemoglobins, is a resource for researchers and clinicians throughout the country and beyond. The laboratory, under the direction of Dr. Abdullah Kutlar and Dr. Ferdane Kutlar, is CAP- and CLIA-certified, fully qualified to offer expert assistance to hemoglobin specialists worldwide.

The center's hemoglobinopathy  laboratory is named in honor of its founder and longtime director, Professor Titus H.J. Huisman. Dr. Huisman died in 1999 but left an indelible legacy as a tireless and devoted researcher.

The expert staff at the Titus H.J. Huisman Hemoglobinopathy Laboratory is ready and eager to serve your hemoglobinopathy testing needs. 

Hemoglobinopathy Testing

Globin Gene Protein-based and DNA-based methods

• Isoelectric Focusing (IEF)

• Quantitative Hemoglobin Testing (HPLC and rp-HPLC)

• Unstable Hemoglobin Screen (Isopropanol)

• Oxygen Affinity Testing (p50)

• Alpha Globin Sequencing

• Beta Globin Sequencing

  Left: Normal Red Blood Cells Right:  Sickled Red Blood Cells

• DNA Sequencing for Unknown Variants

• Deletional Alpha Thalassemias (-3.7, SEA or MED and others)

• Beta Globin Haplotyping

• HPFA Mutation

 

 

Other Testing

• MTHFR (677 and 1298 Mutation)

• Hemochromatosis (HFE C282Y and H63D Mutations)

• Factor V Leiden

• Factor V Rsa Polymorphism

• Prothrombin 20210