Faculty Research

 

Vadivel Ganapathy

Regents' Professor; Ph.D. and Chairman, Madras (India), 1978.  Molecular biology and pathophysiological relevance of plasma membrane transporters; Role of transporters in the kidney, intestinal tract, liver, and the brain; Relevance of transporters to cancer and inflammation; Use of transporters as delivery systems for drugs and prodrugs; Transport of nutrients across the placenta; Human placenta as a target for abusable drugs.
Institutional Faculty List  |  Lab web page

Rashid A. Akhtar
Professor; Ph.D., London, 1975.  Receptor-mediated phospholipid metabolism, generation of second messenger molecules and their role in signal transduction in iris ciliary body and corneal wound healing.
Institutional Faculty List 

Darren Browning
Assistant Professor; Ph.D., University of Toronto, 1995. The functions of cGMP-dependent protein kinase (PKG). Characterization of the role of PKG in tumor biology, including angiogenesis, apoptosis and differentiation. Preclinical studies in animal models compliment in vitro work to establish PKG as a target for the treatment of colon cancer.
Institutional Faculty List  |  Community of Science  |  Browning Lab

Shuang Huang
Associate Professor; Ph.D., Baylor College of Medicine, Houston, Texas, 1994 Understanding the cellular control of cancer cell invasion with a focus on signaling events essential for both cell migration and protease production; therapeutic targets for anti-cancer treatment.
Institutional Faculty List  |  Lab web page

Kebin Liu
Assistant Professor; Ph.D. University of Oklahoma, 1997. Resistance of cancer cells to host immune response; Tumor cell-immune cell interaction, acquisition of apoptosis resistance, and tumor progression; Molecular mechanisms underlying abnormal apoptosis signaling pathways in tumor escape variants.
Institutional Faculty List  |  Community of Science  |  Lab web page
Pamela Moore Martin
Assistant Professor; Ph.D. Medical College of Georgia, 2003. Discovery and analysis of novel biochemical transporters and receptors in retina which may be useful in the development of new therapeutic targets in the treatment and prevention of diabetic retinopathy. Institutional Faculty List

Puttur Prasad
Associate Professor; Ph.D. Indian Inst of Sci. 1992. Nutrient and drug transporters in the placenta. Post-partum depression.

Institutional Faculty List

Keith D. Robertson

Associate Professor and Georgia Cancer Coalition Distinguished Scientist, Ph.D. The Johns Hopkins University, 1996. Epigenetic mechanisms (primarily DNA methylation) that contribute to cancer development and regulate cellular differentiation. Understanding how mammalian DNA methyltransferases (DNMTs) are regulated and targeted throughout the genome. Determining how DNMTs interface with aspects of the histone code (such as histone methylation). Mapping DNA methylation patterns genome-wide in normal and cancerous cells. Connections between DNMTs and DNA damage/DNA repair.  Institutional Faculty List |  Cancer Center web page |  Robertson lab web page
Huidong Shi

Associate Professor; Ph.D. Kyushu Institute of Technology, Fukuoka, Japan 1999. Epigenomics, and development of high-throughput technologies for dissecting the complex epigenetic regulation in normal and tumor cells. Epigenetics can be defined as a heritable change that modulates chromatin organization and gene expression without altering the DNA sequence. While epigenetics refers to the study of single genes or sets of genes, epigenomics is the global analyses of epigenetic changes across the entire genome.

Arun Sreekumar

Assistant Professor; Ph.D. Indian Institute of Science, Bangalore, India 2000 Identification of biomarkers for diagnosis and prognosis of prostate cancer and delineating pathways leading to prostate cancer progression using high-throughput proteomic and metabolomic profiling strategies. Additionally, the laboratory is also interested in characterizing proteins that could predict the response of multiple myeloma patients to clinically relevant therapeutic regimens.

Muthusamy Thangaraju

Assistant Professor; Ph.D. University of Madras, Tamilnadu, India. Role of plasma membrane transporters in the uptake of histone deacetylase (HDAC) inhibitors into tumor cells; Relevance of these transporters to tumor suppression in mammary gland via HDAC inhibition; Physiologic role of these transporters in apoptosis associated with mammary gland involution; Epigenetic mechanisms responsible for silencing of these transporters in breast cancer.

Institutional Faculty List

Stuart A. Thompson
Associate Professor; Ph.D., The University of North Carolina at Chapel Hill, 1992. Understanding bacterial gene regulation events (including epigenetic regulation) that occur during infection of humans by the gastrointestinal pathogen Campylobacter jejuni; characterizing C. jejuni virulence factors; development of a vaccine against C. jejuni infection.
Institutional Faculty List  |  Community of Science  |  Lab web page

Dorothy Tuan
Professor; Ph.D., California Institute of Technology. 

Transcriptional control of globin gene expression; mechanism of globin gene switching during erythroid differentiation; application to gene therapy for sickle cell disease and thalassemia; biological function of ERV-9 human endogenous retrovirus in long-range gene regulation.

Institutional Faculty List 

 

Faculty with Joint Appointments in BMB:

Anil Govind Cashikar
Assistant Professor, Ph.D. Department of Radiology, Protein aggregation in human disease specifically in neurodegeneration and cancer.
Faculty Information Page

William Dynan
Professor of Medicine, Ph.D.  Institute of Molecular Medicine and Genetics.   DNA-dependent protein kinase.
Institutional Faculty List 

Abdullah Kutlar
Associate Professor.  Medicine.  Thallasemias.  Globin gene regulation.
Institutional Faculty List 

Greg Liou
Associate Professor, Ph.D. Department of Ophthalmology. Regulation of gene expression in the retina.
Institutional Faculty List  |  Community of Science

Demetrius Moskophidis
Associate Professor, M.D.  Institute of Molecular Medicine and Genetics.   Program in Molecular Immunology.  Immune response to viral infection.
Institutional Faculty List 

 

Adjunct Faculty in BMB:

M. Stephen Trent
Associate Professor; Ph.D., East Tennessee State University, 1998.

Emeritus Faculty in BMB:

Ata Abdel-Latif
Regent's Professor Emeritus; Ph D.,  IL Inst of Tech, 1963
Institutional Faculty List

Frederick H. Leibach
Professor and Chairman Emeritus; Ph D., Emory University, 1964.   Regulation of metabolic processes and transport systems in kidney and intestine; biochemistry and physiology of amino acid and peptide transporters of the mammalian cell plasma membrane.
Institutional Faculty List  |  Community of Science

 

 

Revised November 18, 2009 .   Please send comments, suggestions or questions about this page to Stuart Thompson, stthompson@mcg.edu .