Publications

• Gladysheva IP, King SM, Houng AK N-glycosylation modulates the cell surface expression and catalytic activity of corin. Biochem. Biophys. Research Commun. 2008, 373, 130-135.
• Gladysheva IP, Robinson BR, Houng AK, Kováts T, King SM Corin is co-expressed with pro-ANP and localized on the cardiomyocyte surface in both zymogen and catalytically active forms. Journal of Molecular and Cellular Cardiology. 2008, 44(1), 131-142.
• Sazonova IY, Thomas BM, Gladysheva IP, Houng AK, Reed, GL. Fibrinolysis is amplified by converting a2-antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis. 2007, 5 (10), 2087-2094.
• Ibebuogu UN, Thornton JW, Reed GL. An unusual case of peripartum cardiomyopathy manifesting with multiple thrombo-embolic phenomena. Thromb J. 2007 Oct 29;5(1):18 [Epub ahead of print] PMID: 17967197.
• Huggins GS, Lepore JJ, Greytak S, Patten R, McNamee R, Aronovitz M, Wang PJ, Reed GL. The CREB leucine zipper regulates CREB phosphorylation, cardiomyopathy, and lethality in a transgenic model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1877-82.
• Gladysheva IP, Sazonova IY, Houng A, Hedstrom L, Reed GL. Regulation of nonproteolytic active site formation in plasminogen. Biochemistry. 2007 Jul 31;46(30):8879-87.
• Nahrendorf M, Hu K, Frantz S, Jaffer FA, Tung CH, Hiller KH, Voll S, Nordbeck P, Sosnovik D, Gattenlohner S, Novikov M, Dickneite G, Reed GL, Jakob P, Rosenzweig A, Bauer WR, Weissleder R, Ertl G. Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction. Circulation. 2006 Mar 7;113(9):1196-202.
• Reed GL. Platelet secretory mechanisms. Semin Thromb Hemost. 2004 Aug;30(4):441-50. Review.
• Jaffer FA, Tung CH, Wykrzykowska JJ, Ho NH, Houng AK, Reed GL, Weissleder R. Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombi. Circulation. 2004 Jul 13;110(2):170-6. Epub 2004 Jun 21.
• Sazonova IY, Robinson BR, Gladysheva IP, Castellino FJ, Reed GL. alpha Domain deletion converts streptokinase into a fibrin-dependent plasminogen activator through mechanisms akin to staphylokinase and tissue plasminogen activator. J Biol Chem. 2004 Jun 11;279(24):24994-5001.
• Polgar J, Lane WS, Chung SH, Houng AK, Reed GL. Phosphorylation of SNAP-23 in activated human platelets. J Biol Chem. 2003 Nov 7;278(45):44369-76.
• Tung CH, Ho NH, Zeng Q, Tang Y, Jaffer FA, Reed GL, Weissleder R. Novel factor XIII probes for blood coagulation imaging. Chembiochem. 2003 Sep 5;4(9):897-9.
• Gladysheva IP, Turner RB, Sazonova IY, Liu L, Reed GL. Coevolutionary patterns in plasminogen activation. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9168-72.
• Reed GL. Good breeding matters: in-bred rodents provide genetic insights into platelet secretion. Thromb Haemost. 2003 Jun;89(6):951-2.
• Houng A, Polgar J, Reed GL. Munc18-syntaxin complexes and exocytosis in human platelets. J Biol Chem. 2003 May 30;278(22):19627-33.
• Turner RB, Liu L, Sazonova IY, Reed GL. Structural elements that govern the substrate specificity of the clot-dissolving enzyme plasmin. J Biol Chem. 2002 Sep 6;277(36):33068-74.
• Polgar J, Chung SH, Reed GL. Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. Blood. 2002 Aug 1;100(3):1081-3.
• King SM, Reed GL. Development of platelet secretory granules. Semin Cell Dev Biol. 2002 Aug;13(4):293-302. Review.
• Gladysheva IP, Sazonova IY, Chowdhry SA, Liu L, Turner RB, Reed GL. Chimerism reveals a role for the streptokinase Beta -domain in nonproteolytic active site formation, substrate, and inhibitor interactions. J Biol Chem. 2002 Jul 26;277(30):26846-51.
• Dale GL, Friese P, Batar P, Hamilton SF, Reed GL, Jackson KW, Clemetson KJ, Alberio L. Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface. Nature. 2002 Jan 10;415(6868):175-9.
• Reed GL, Fitzgerald ML, Polgar J. Molecular mechanisms of platelet exocytosis: insights into the "secrete" life of thrombocytes. Blood. 2000 Nov 15;96(10):3334-42. Review.