The Layman Lab
Research Page

Our laboratory is interested in genes involved in human puberty and reproduction. Humans with delayed puberty due to idiopathic hypogonadotropic hypogonadism (IHH) and patients experiencing infertility are being charaterized clinically and studied for mutations in reproductive genes. Identified mutations are then studied in vitro to determine their functional effects and further genotype/phenotype correlations are made. Mutations have been identified and characterized in genes including GNRHR, FSHB, and KAL1, among others. Human, mouse, and zebrafish models are being exploited to further understand normal hypothalamic-pituitary gonadal axis development and function with regard to normal puberty and fertility.

Copyright 2005
Medical College of Georgia
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Please email comments, suggestions or questions to:
Laura Hutcheson, ljhutche@mcg.edu

December 12, 2005