A-Z Index  |  MCG Home  |  Site Search 

Selected Publications:

Ko, L., Cardona, G.R. and Chin, W.W. (2000) Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator. Proc. Natl. Acad. Sci. USA 97: 6212-6217. [PDF]

Iwasaki, T., Chin, W.W., Ko, L. (2001) Identification and characterization of an RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM). J. Biol. Chem. 276:33375-33383. [PDF]

Ko, L., Cardona, G.R., Iwasaki, T., Bramlett, K.S., Burris, T.P. and Chin, W.W. (2002) Ser884 adjacent to the LXXLL motif of coactivator TRBP defines selectivity for estrogen receptors and thyroid hormone receptor. Mol. Endocrinol. 16:128-140. [PDF]

Ko, L., Cardona, G.R. Henrion, A. and Chin, W.W. (2002) Identification of a tissue-specific coactivator GT198 that interacts with the DNA-binding domain of nuclear receptors. Mol. Cell. Biol. 22:357-369. [PDF]

Kuang, S. Q., Liao, L., Zhang, H., Pereira, F. A., Yuan, Y., DeMayo, F. J., Ko, L. and Xu, J. (2002) Deletion of the cancer-amplified coactivator AIB3/TRBP results in defective placentation and embryonic lethality. J. Biol. Chem. 277: 45356-45360.  [PDF]

Ko, L. and Chin, W.W. (2003) Nuclear receptor coactivator TRBP interacts and stimulates its associated DNA-dependent protein kinase. J. Biol. Chem. 78:11471-11479. [PDF]

Auboeuf, D., Dowhan, D.H., Li, X., Larkin, K., Ko, L., Berget, S. M., and O'Malley, B. W. (2004) CoAA: A nuclear receptor coactivator protein at the interface of transcriptional coactivator and RNA Splicing. Mol. Cell. Biol. 24:442-453. [PDF]

Sui, Y., Yang, Z., Xiong, S., Zhang, L., Blanchard, K.L., Peiper, S.C., Dynan, W.S., Tuan, D. and Ko, L. (2007) Gene amplification and associated loss of 5' regulator sequences of CoAA in human cancers. Oncogene 26:822-835

Yang, Z., Sui, Y., Xiong, S., Liour, S.S., Phillips, A.C. and Ko, L. (2007) Switched Alternative Splicing of Oncogene CoAA during Embryonal Carcinoma Stem Cell Differentiation.  Submitteed to Nucleic Acids Res 35;19919-1932