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Dynan Lab

Selected Publications:

Jovanovic M, Dynan WS. Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis.  Nucleic Acids Res. 2006 Feb 18;34(4):1112-20.
Bladen CL, Lam WK, Dynan WS, Kozlowski DJ. DNA damage response and Ku80 function in the vertebrate embryo.  Nucleic Acids Res. 2005 May 24;33(9):3002-10. [ABSTRACT | FULL TEXT]

Greengauz-Roberts O, Stopper H, Nomura S, Yamaguchi H, Goldenring JR, Podolsky RH, Lee JR, Dynan WS. Saturation labeling with cysteine-reactive cyanine fluorescent dyes provides increased sensitivity for protein expression profiling of laser-microdissected clinical specimens. Proteomics. 2005 Mar 10; [Epub ahead of print]. [ABSTRACT | FULL TEXT]

Bladen CL, Udayakumar D, Takeda Y, Dynan WS. Identification of the polypyrimidine tract binding protein-associated splicing factor.p54(nrb) complex as a candidate DNA double-strand break rejoining factor. J Biol Chem. 2005 Feb 18;280(7):5205-10. Epub 2004 Dec 7. [ABSTRACT | FULL TEXT]

Lee KJ, Jovanovic M, Udayakumar D, Bladen CL, Dynan WS. Identification of DNA-PKcs phosphorylation sites in XRCC4 and effects of mutations at these sites on DNA end joining in a cell-free system. DNA Repair (Amst). 2004 Mar 4;3(3):267-76. [FULL TEXT]

Udayakumar, D., Bladen, C.L., Hudson, F.Z., and Dynan, W.S.
Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase phosphorylation. J. Biol. Chem. 278:41631-41635 (2003). [ABSTRACT | FULL TEXT]

Li, S., Takeda, Y, Wragg, S., Barrett, J, Phillips, A., and Dynan, W. S. Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase. Nucleic Acids Res. 31:5848-5857 (2003). [ABSTRACT | FULL TEXT]

Mo, X., and Dynan, W.S. “Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites.” Molec. and Cell. Biol 22:8088-8099 (2002). [ABSTRACT | FULL TEXT]


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Medical College of Georgia
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Please email comments, suggestions or questions to:
Laura Hutcheson, ljhutche@mcg.edu

May 8, 2005