Publications and Acknowledgments

The Mouse ES Cell and Transgenesis Core Facility requests that investigators, as a condition of service, acknowledge the Core and the services provided by the Core in any ‘primary’ publication (i.e. the first peer-reviewed publication in which cells or mice generated, at least in part, through the services of the Core are described or employed) and/or in all other forms of public or private dissemination of information (seminars, abstracts, advertisements, etc.).  An appropriate form of words might be, for example: xxx targeted mice were generated with the services of the Medical College of Georgia Mouse ES Cell and Transgenesis Core Facility.  This information is important to future planning of the Core, which is heavily reliant on Institutional subsidies.  If you have any new information about ‘primary’ publications, please let the Core know by sending an email to the Director.

A partial list of ‘primary’ publications arising from services provided by the Medical College of Georgia Mouse ES Cell and Transgenesis Core Facility is presented below.

1.    Li X, Yonenaga Y, Seki T: Shortened ALK1 regulatory fragment maintains a specific activity in arteries feeding ischemic tissues. Gene Ther 16(8):1034, 2009.

2.    Pacholczyk G, Suhag R, Mazurek M, Dederscheck SM, Koni PA: Generation of C57BL/6 knockout mice using C3H x BALB/c blastocysts. Biotechniques 44(3):413, 2008.

3.    Pacholczyk R, Kern J, Singh N, Iwashima M, Kraj P, Ignatowicz L: Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells. Immunity 27(3):493, 2007.

4.    Huang L, Min JN, Masters S, Mivechi NF, Moskophidis D: Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption. Genesis 45(8):487, 2007.

5.    Gordon J, Xiao S, Hughes B, 3rd, Su DM, Navarre SP, Condie BG, Manley NR: Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus. BMC Dev Biol 7:69, 2007.

6.    Keskintepe L, Norris K, Pacholczyk G, Dederscheck SM, Eroglu A: Derivation and comparison of C57BL/6 embryonic stem cells to a widely used 129 embryonic stem cell line. Transgenic Res Online First 16 August, 2007.

7.    Liang S, Zhang W, Horuzsko A: Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. Eur J Immunol 36(9):2457, 2006.

8.    Shimoda M, Mmanywa F, Joshi SK, Li T, Miyake K, Pihkala J, Abbas JA, Koni PA: Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance. J Immunol 176(11):6503, 2006.

9.    Kim J, Lauderdale JD: Analysis of Pax6 expression using a BAC transgene reveals the presence of a paired-less isoform of Pax6 in the eye and olfactory bulb. Dev Biol 292(2):486, 2006.

10.  Pacholczyk R, Ignatowicz H, Kraj P, Ignatowicz L: Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells. Immunity 25(2):249, 2006.

11.  Shimoda M, Li T, Pihkala JP, Koni PA: Role of MHC class II on memory B cells in post-germinal center B cell homeostasis and memory response. J Immunol 176(4):2122, 2006.

12.  Ristich V, Liang S, Zhang W, Wu J, Horuzsko A: Tolerization of dendritic cells by HLA-G. Eur J Immunol 35(4):1133, 2005.

13.  Min JN, Zhang Y, Moskophidis D, Mivechi NF: Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation. Genesis 40(4):205, 2004.

14.  Wang G, Zhang J, Moskophidis D, Mivechi NF: Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis. Genesis 36(1):48, 2003.

15.  Su DM, Navarre S, Oh WJ, Condie BG, Manley NR: A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation. Nat Immunol 4(11):1128, 2003.

16.  Mellor AL, Baban B, Chandler P, Marshall B, Jhaver K, Hansen A, Koni PA, Iwashima M, Munn DH: Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion. J Immunol 171(4):1652, 2003.

17.  Sullivan BA, Kraj P, Weber DA, Ignatowicz L, Jensen PE: Positive selection of a Qa-1-restricted T cell receptor with specificity for insulin. Immunity 17(1):95, 2002.

18.  Zhang Y, Huang L, Zhang J, Moskophidis D, Mivechi NF: Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue-specific regulation for stress-inducible Hsp molecular chaperones. J Cell Biochem 86(2):376, 2002.

19.  Hashimoto K, Joshi SK, Koni PA: A conditional null allele of the major histocompatibility IA-beta chain gene. Genesis 32(2):152, 2002.

20.  Koushik SV, Chen H, Wang J, Conway SJ: Generation of a conditional loxP allele of the Pax3 transcription factor that enables selective deletion of the homeodomain. Genesis 32(2):114, 2002.

21.  Westmoreland JJ, Hancock CR, Condie BG: Neuronal development of embryonic stem cells: a model of GABAergic neuron differentiation. Biochem Biophys Res Commun 284(3):674, 2001.

22.  Kraj P, Pacholczyk R, Ignatowicz H, Kisielow P, Jensen P, Ignatowicz L: Positive selection of CD4(+) T cells is induced in vivo by agonist and inhibited by antagonist peptides. J Exp Med 194(4):407, 2001.

23.  Pacholczyk R, Kraj P, Ignatowicz L: An incremental increase in the complexity of peptides bound to class II MHC changes the diversity of positively selected alpha beta TCRs. J Immunol 166(4):2357, 2001.

24.  Koushik SV, Wang J, Rogers R, Moskophidis D, Lambert NA, Creazzo TL, Conway SJ: Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization. Faseb J 15(7):1209, 2001.

25.  Huang L, Mivechi NF, Moskophidis D: Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene. Mol Cell Biol 21(24):8575, 2001.

26.  Kraj P, Pacholczyk R, Ignatowicz L: Alpha beta TCRs differ in the degree of their specificity for the positively selecting MHC/peptide ligand. J Immunol 166(4):2251, 2001.