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Small Animal Behavior Core Laboratory
Services
Description: In the grip strength test, the rodent is held by the
nape of its neck and the base of its tail. Its forelimbs are placed on the
tension bar and the rat is gently pulled back until it releases the bar. The
distance the rodent pulls the bar before it releases its paw-grip is
measured in kilograms of resistance by a strain gauge. Hindlimb strength can
also be assessed.
Purpose: The purpose of the grip strength test is to evaluate the
strength of forelimb and hind limb muscles. This test is useful in detecting
changes in motor function and muscle strength associated with drugs or other
manipulations.